Background: Gamma knife stereotactic radiosurgery (SRS) has become an important management strategy for patients with meningiomas. Although prior reports have studied early tumor control, neurological response, and associated morbidity, our purpose was to use clinical and imaging studies to determine whether long-term outcomes remain stable over time. Introduction: Gamma Knife radiosurgery (GKRS) has been established as a safe and effective treatment option for trigeminal neuralgia. Some patients have contraindications to magnetic resonance imaging (MRI), the standard stereotactic imaging used for GKRS treatment planning. Meningioma is the most frequent benign tumor treated with Gamma Knife surgery (GKS); however, the assessment of its efficacy and safety in slow-growing tumors is an ongoing process, requiring analysis of long-term results. Three hundred sixty-eight patients harboring 400 meningiomas treated between 1992 and 1999 at Na Homolce Hospital were Gamma Knife surgery is a safe and effective treatment over the long term in selected patients with cavernous sinus meningiomas. Tumor progression is more likely to occur from the lesion margin outside the treatment volume. In small to medium-sized tumors, GKS is an excellent alternative to resection … Patients can immediately resume activities. • No hair is shaved. • Eliminates risk of infection, blood clots, hemorrhaging, brain swelling, prolonged (though temporary) facial weakness/paralysis and permanent facial weakness/paralysis. • The cost is often 20% to 35% less than conventional neurosurgery. The Gamma Knife allows surgeons to perform brain surgery without opening the skull, and the affected tissue can be targeted with extreme precision, while sparing the surrounding healthy tissues. Because a surgical incision is not required, the risks associated with open brain surgery, including acute hemorrhage, spinal fluid leakage and 3R9ed.

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